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The comprehensive report itemizes a number of pathways through which the chemicals in tobacco smoke damage the human body and lead to disease and death.

There are more than 7,000 chemicals in tobacco smoke, which the HHS describes as a "deadly" mixture containing hundreds of toxic substances, and at least 70 known to cause cancer.

http://www.surgeongeneral.gov/library/tobaccosmoke/index.html

 
Published online 6 December 2010 | Nature | doi:10.1038/468742a

Basel Declaration defends animal research

Animal activists last summer set fire to the alpine holiday home of Daniel Vasella, then chief executive of pharmaceutical giant Novartis of Basel, Switzerland, in one of relatively few violent attacks on scientists working with animals in German-speaking countries.

But in the past few years these scientists have been feeling the pressure in other ways — from animal activists who have attempted to publicly shame them or have sent threatening e-mails, and from legislation that increasingly restricts the use of animals in basic research.

Now, in a bid to reverse that trend, more than 50 top scientists working in Germany and Switzerland have launched an education offensive. Meeting in Basel on 29 November, they drafted and signed a declaration pledging to be more open about their research, and to engage in more public dialogue.

"The public tends to have false perceptions about animal research, such as thinking they can always be replaced by alternative methods like cell culture," says Stefan Treue, director of the German Primate Center in Göttingen. Treue co-chaired the Basel meeting, called 'Research at a Crossroads', with molecular biologist Michael Hengartner, dean of science at the University of Zurich, Switzerland. Outreach activities, such as inviting the public into universities to talk to scientists about animal research, "will be helpful to both sides".

Read more at http://www.nature.com/news/2010/101206/full/468742a.html?s=news_rss